SY
Spyre Therapeutics Inc.
SYRE · Spyre Therapeutics Inc. · Healthcare
Up next day
7/11
64%
Fell despite growth
2/11
Good earnings ignored
Avg earnings move
±3.7%
typical swing on earnings
Price when beating
+0.4%
avg over 3 beats
Biggest single move
+9.0%
'23.12 · largest reaction
How this stock reacts to earnings
Traits seen across its recent earnings reactions
Good results usually push the stock up
Up the next day 2 of 3 beats (67%)
Reaction is erratic and hard to predict
Avg +0.4% on a beat, +1.2% on a miss
Tends to keep drifting the same way for days
Day-one direction continued · 64% of last 11
vs Healthcare sector avg (153 peers)
This
+1.0%
Sector
+0.4%
Avg next-day reaction
Earnings number vs guidance — which drives it?
How often the beat/miss matched the actual price move
This stock reacts more to guidance & expectations than the reported number
Moved opposite to results 6 of last 11 times (55%)
1xBeat but fell
Even a beat sells off if guidance disappoints
5xMissed but rose
Even a miss rebounds if guidance reassures
Earnings timeline · tap a bar for that quarter
Nov 3After close
'26.7 expectedEst. EPS $-0.81
Quarter ended 3/2026
Reported 2026-05-05
Next-day move
+2.8%
After 5 days +5.7%
vs Consensus$-0.65→$-0.74-13.1% miss
Missed by -13.1% but stock +2.8%
EPS
$-0.74
YoY -23%
Revenue
—
Next-Q guidance
—
N/A
Price around earnings
+113% run-up before
Earnings trend · last 12 quarters
EPS$-0.74YoY -23%
'22.3'26.3
Revenue—
'22.3'26.3
Price vs earnings · last 12 quarters
↑Up↓Down
Bad news out
weak · up ↑
2x18%
Met expectations
good · up ↑
5x45%
Disappointment
weak · down ↓
2x18%
Good earnings ignored
good · down ↓
2x18%
← ← Weak earningsStrong earnings → →
Mostly 'honest' — good earnings, price up · 5 of 11q (45%)
Community · SYRE
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